The article from the National Center for Biotechnology Information discusses the Peptide Nucleic Acid (PNA) and its applications in molecular biology.

Zhè piān wénzhāng láizì guójiā shēngwù jìshù xìnxī zhōngxīn, tǎolùnle tài hé suān (PNA) jí qí zài fēnzǐ shēngwùxué zhōng de yìngyòng.

这篇文章来自国家生物技术信息中心，讨论了肽核酸（PNA）及其在分子生物学中的应用。

PNAs are synthetic analogs of DNA and RNA, characterized by a peptide-like backbone that makes them more stable and resistant to enzymatic degradation.

PNA shì DNA hé RNA de héchéng lèisìwù, qí tèzhēng shì tài yàng de zhǔ liàn, shǐ qí gèng wěndìng qiě duì méi jiàngjiě jùyǒu kàngxìng.

PNA是DNA和RNA的合成类似物，其特征是肽样的主链，使其更稳定且对酶降解具有抗性。

This stability allows PNAs to bind strongly to complementary nucleic acid sequences, making them valuable tools for studying gene expression, genetic diseases, and developing diagnostic methods.

Zhè zhǒng wěndìngxìng shǐ PNA nénggòu qiángliè jiéhé hùbǔ de hésuān xùliè, shǐ qí chéngwéi yánjiū jīyīn biǎodá, yíchuán jíbìng hé kāifā zhěnduàn fāngfǎ de bǎoguì gōngjù.

这种稳定性使PNA能够强烈结合互补的核酸序列，使其成为研究基因表达、遗传疾病和开发诊断方法的宝贵工具。

PNAs have been utilized in various applications, including antisense therapy, where they can inhibit the expression of target genes, and in the development of molecular probes for detecting specific DNA or RNA sequences in cells.

PNA yǐ zài gè zhǒng yìngyòng zhōng shǐyòng, bāokuò fǎnyì liáofǎ, zài zhè zhǒng liáofǎ zhōng, tāmen kěyǐ yìzhì mùbiāo jīyīn de biǎodá, bìng zài kāifā jiǎncè xìbāo zhōng tèdìng DNA huò RNA xùliè de fēnzǐ tànzhēn fāngmiàn shǐyòng.

PNA已在各种应用中使用，包括反义疗法，在这种疗法中，它们可以抑制目标基因的表达，并在开发检测细胞中特定DNA或RNA序列的分子探针方面使用。

Their unique properties enable PNAs to detect mutations and polymorphisms with high specificity, making them useful in diagnostic assays and for understanding genetic variations associated with diseases.

Tāmen dútè de shǔxìng shǐ PNA nénggòu yǐ gāo tèyìxìng jiǎncè túbiàn hé duōtài xìng, shǐ qí zài zhěnduàn jiǎncè hé lǐjiě yǔ jíbìng xiāngguān de yíchuán biànyì fāngmiàn fēicháng yǒu yòng.

它们独特的属性使PNA能够以高特异性检测突变和多态性，使其在诊断检测和理解与疾病相关的遗传变异方面非常有用。

Overall, PNAs represent a versatile technology in the field of genetics and molecular diagnostics, offering advantages over traditional nucleic acid-based methods due to their enhanced stability and binding properties.

Zǒngtǐ ér yán, PNA zài yíchuánxué hé fēnzǐ zhěnduàn lǐngyù dàibiǎole yī zhǒng duōgōngnéng de jìshù, yóuyú qí zēngqiáng de wěndìngxìng hé jiéhé tèxìng, tígōngle yōuyú chuántǒng hésuān jīchǔ fāngfǎ de yōushì.

总体而言，PNA在遗传学和分子诊断领域代表了一种多功能的技术，由于其增强的稳定性和结合特性，提供了优于传统核酸基础方法的优势。