The article 'Metformin: A Review of its Effects on the Gastrointestinal System' focuses on the gastrointestinal (GI) effects of metformin, a widely used oral medication for type 2 diabetes.

Wénzhāng ‘èrjiǎ shuāngguā: duì wèi cháng xìtǒng yǐngxiǎng de zōngshù’ zhòngdiǎn guānzhù èrjiǎ shuāngguā de wèi cháng (GI) xiàoguǒ, zhè shì yī zhǒng guǎngfàn shǐyòng de kǒufū tángniàobìng yàowù.

文章《二甲双胍：对胃肠系统影响的综述》重点关注二甲双胍的胃肠（GI）效果，这是一种广泛使用的口服糖尿病药物。

While metformin is primarily known for its glucose-lowering effects, the article highlights its various impacts on the GI system, including potential benefits and adverse effects.

Suīrán èrjiǎ shuāngguā zhǔyào yǐ qí jiàngtáng xiàoguǒ ér wénmíng, dàn běnwén qiángdiào le qí duì wèi cháng xìtǒng de gèzhǒng yǐngxiǎng, bāokuò qiánzài de hǎochù hé bùliáng yǐngxiǎng.

虽然二甲双胍主要以其降糖效果而闻名，但本文强调了其对胃肠系统的各种影响，包括潜在的好处和不良影响。

Common side effects such as gastrointestinal discomfort, diarrhea, and nausea are noted, which can affect patient adherence to the medication.

Chángjiàn de fùzuòyòng bāokē wèi cháng bùshì, fùxiè hé èxīn, zhè kěnéng yǐngxiǎng huànzhě duì yàowù de yīcóng xìng.

常见的副作用包括胃肠不适、腹泻和恶心，这可能影响患者对药物的依从性。

The review delves into the mechanisms behind these GI effects, suggesting that metformin influences gut microbiota, enhances intestinal glucose absorption, and may stimulate the release of certain hormones.

Gāi zōngshù shēnrù tàntǎo le zhèxiē wèi cháng xiàoguǒ bèihòu de jīzhì, biǎomíng èrjiǎ shuāngguā yǐngxiǎng chángdào wēishēngwùqún, zēngqiáng chángdào duì pútáotáng de xīshōu, bìng kěnéng cìjī mǒuxiē jīsù de shìfàng.

该综述深入探讨了这些胃肠效果背后的机制，表明二甲双胍影响肠道微生物群，增强肠道对葡萄糖的吸收，并可能刺激某些激素的释放。

It also discusses how metformin can lead to beneficial outcomes such as weight loss and enhanced gut health, potentially reducing the risk of diabetes complications.

Tā hái tǎolùn le èrjiǎ shuāngguā rúhé dǎozhì yǒuyì de jiéguǒ, rú jiǎnqīng tǐzhòng hé gǎishàn chángdào jiànkāng, kěnéng jiàngdī tángniàobìng bìngfāzhèng de fēngxiǎn.

它还讨论了二甲双胍如何导致有益的结果，如减轻体重和改善肠道健康，可能降低糖尿病并发症的风险。

Overall, the article underscores the complex role of metformin in influencing the gastrointestinal system, emphasizing the need for healthcare providers to be aware of these effects to manage patient care effectively and improve adherence to treatment for individuals with type 2 diabetes.

Zǒngtǐ ér yán, wénzhāng qiángdiào le èrjiǎ shuāngguā zài yǐngxiǎng wèi cháng xìtǒng zhōng de fùzá zuòyòng, qiángdiào yīliáo fúwù tígōng zhě xūyào yìshí dào zhèxiē yǐngxiǎng, yǐ yǒuxiào guǎnlǐ huànzhě hùlǐ bìng tígāo duì 2 xíng tángniàobìng huànzhě de zhìliáo yīcóng xìng.

总体而言，文章强调了二甲双胍在影响胃肠系统中的复杂作用，强调医疗服务提供者需要意识到这些影响，以有效管理患者护理并提高对2型糖尿病患者的治疗依从性。